Polynucleotide Complex – Topical Grade (Sodium Polynucleotide) is a Polynucleotide supplied by MakeYourSkin as powder / liquid for professional cosmetic formulation. A Korean-beauty staple, it is valued for hydration, conditioning, regenerative positioning.

What is Polynucleotide Complex – Topical Grade?

Polynucleotide Complex – Topical Grade is supplied under the INCI / technical name Sodium Polynucleotide.

It belongs to the Polynucleotide group and is derived from salmon or trout milt derived. The material reaches you as powder / liquid. It sits in the high-growth band of the 2025–2026 market, which means supply, pricing and claim substantiation are all moving quickly — confirm current availability before committing to a launch date.

Key Properties & Benefits

• Hydration
• Conditioning
• Regenerative positioning
• Supplied cosmetic grade with a Certificate of Analysis for every batch.

Uses & Applications

Polynucleotide Complex – Topical Grade is used in anti-ageing serums, eye creams, night creams, ampoules, neck and décolleté treatments and firming body products.

Typical applications from the catalogue record: Premium ampoules, post-procedure care.

In leave-on skincare it is normally dosed into a serum, ampoule or moisturiser where contact time is long enough for the claim to hold up. In rinse-off formats it is used at a lower level for label presence and sensory contribution rather than measurable performance. In Korean and Japanese formats it suits essences, toner pads, sheet-mask serums and lightweight gel-creams, where thin, layerable textures are the norm.

How to Use — Recommended Use Level

No single published use level applies to every grade of this material, so the figure above is a general starting rule rather than a specification.

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

Technical Notes

The single hottest K-beauty ingredient story of 2025–2026. Cosmetic claims only — injectable evidence does not transfer.

Regulatory Note

Supplier diligence required: High diligence: source species, molecular weight, purity, claims and jurisdiction-specific review.

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

• Certificate of Analysis (CoA) for the batch supplied
• Safety Data Sheet (SDS / MSDS) in the current GHS format
• Technical Data Sheet (TDS) with specification, solubility and handling guidance
• INCI declaration and, where assigned, CAS / EINECS numbers
• Non-GMO statement on request
• Vegan / animal-origin declaration on request
• Halal and Kosher certification on request where the supplier holds it
• Heavy-metal and microbiological test data on request

Available Pack Sizes

This is a high-value material, so it is supplied on our small-pack ladder: 10 g, 50 g, 100 g and 1 Kg. Larger quantities are quoted on request — contact the MakeYourSkin sales desk for availability, lead time and a firm price.

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.

Restricted or high-diligence material. Confirm your legal position in every destination market before ordering. Supplied on the understanding that the buyer holds responsibility for compliant use, permitted concentration and claim wording.