PDRN / Sodium DNA (Sodium DNA) is a Polynucleotide supplied by MakeYourSkin as powder / filtrate / oil / concentrate depending material for professional cosmetic formulation. A Korean-beauty staple, it is valued for regenerative / hydration positioning.

What is PDRN / Sodium DNA?

PDRN / Sodium DNA is supplied under the INCI / technical name Sodium DNA and carries CAS number 68938-01-2.

It belongs to the Polynucleotide group and is available from botanical, ferment, biotech or marine routes depending on the grade ordered. The material reaches you as powder / filtrate / oil / concentrate depending material. It sits in the high-growth band of the 2025–2026 market, which means supply, pricing and claim substantiation are all moving quickly — confirm current availability before committing to a launch date.

Key Properties & Benefits

• Regenerative / hydration positioning
• Supplied cosmetic grade with a Certificate of Analysis for every batch.

Uses & Applications

PDRN / Sodium DNA is used in essences, ampoules, sheet masks, cushion formulas, toner pads and gel-creams.

Typical applications from the catalogue record: Serums, essences, masks, creams, scalp/hair as relevant.

In Korean and Japanese formats it suits essences, toner pads, sheet-mask serums and lightweight gel-creams, where thin, layerable textures are the norm.

Handling note: Add to the oil phase and protect from prolonged heat and air exposure.

How to Use — Recommended Use Level

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

Regulatory Note

Polynucleotide and salmon-DNA materials are positioned for topical cosmetic use only. Evidence generated for injectable or medical-device PDRN does not transfer to a topical cosmetic. Confirm the exact INCI, source species, molecular-weight profile, purity and residual-protein data, and keep all claims cosmetic.

Supplier diligence required: Emerging / high regulatory and safety diligence; market-specific.

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

• Certificate of Analysis (CoA) for the batch supplied
• Safety Data Sheet (SDS / MSDS) in the current GHS format
• Technical Data Sheet (TDS) with specification, solubility and handling guidance
• INCI declaration and, where assigned, CAS / EINECS numbers
• Non-GMO statement on request
• Vegan / animal-origin declaration on request
• Halal and Kosher certification on request where the supplier holds it
• Heavy-metal and microbiological test data on request

Available Pack Sizes

Supplied in 50 g, 225 g, 1 Kg and 5 Kg packs. Bulk quantities above 5 Kg, and drum or sack quantities, are available on request — contact the MakeYourSkin sales desk for a quotation and lead time.

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.