Natto Polyglutamic Acid (Polyglutamic Acid) is a Fermentation polymer supplied by MakeYourSkin as powder / filtrate / oil / concentrate depending material for professional cosmetic formulation. Drawn from the Japanese beauty tradition, it is valued for hydration.

What is Natto Polyglutamic Acid?

Natto Polyglutamic Acid is supplied under the INCI / technical name Polyglutamic Acid and carries CAS number 25513-46-6.

It belongs to the Fermentation polymer group and is available from botanical, ferment, biotech or marine routes depending on the grade ordered. The material reaches you as powder / filtrate / oil / concentrate depending material. It sits in the high-growth band of the 2025–2026 market, which means supply, pricing and claim substantiation are all moving quickly — confirm current availability before committing to a launch date.

Key Properties & Benefits

• Hydration
• Produced by a controlled fermentation process with a defined organism and substrate.

Uses & Applications

Natto Polyglutamic Acid is used in Japanese-style lotions, milky essences, cleansing oils, sunscreens and layering serums.

Typical applications from the catalogue record: Serums, essences, masks, creams, scalp/hair as relevant.

In Korean and Japanese formats it suits essences, toner pads, sheet-mask serums and lightweight gel-creams, where thin, layerable textures are the norm.

Handling note: Add to the oil phase and protect from prolonged heat and air exposure.

How to Use — Recommended Use Level

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

Regulatory Note

Ferment filtrates and lysates require a defined substrate, organism, process and inactivation step, plus a microbiological specification and the preservative system used in the material itself. Confirm the exact INCI and that the organism is acceptable in the destination market.

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

• Certificate of Analysis (CoA) for the batch supplied
• Safety Data Sheet (SDS / MSDS) in the current GHS format
• Technical Data Sheet (TDS) with specification, solubility and handling guidance
• INCI declaration and, where assigned, CAS / EINECS numbers
• Non-GMO statement on request
• Vegan / animal-origin declaration on request
• Halal and Kosher certification on request where the supplier holds it
• Heavy-metal and microbiological test data on request

Available Pack Sizes

Supplied in 50 g, 225 g, 1 Kg and 5 Kg packs. Bulk quantities above 5 Kg, and drum or sack quantities, are available on request — contact the MakeYourSkin sales desk for a quotation and lead time.

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Low-pH material. Can cause burns to skin and eyes in concentrated form. Add to water, never water to acid; neutralise carefully and confirm the final pH of the finished product. Products formulated at low pH increase sun sensitivity — a daily sunscreen instruction is expected on the finished pack.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.

Heat-sensitive. Add at cool-down below the temperature stated on the technical data sheet; exceeding it degrades the active and can change colour and odour.