Hydroxyectoin — powder, Global — MakeYourSkin

About this material

Hydroxyectoin is an Extremolyte supplied by MakeYourSkin as powder / liquid depending grade for professional cosmetic formulation. Used worldwide across mainstream cosmetic formulation, it is valued for stress protection, hydration.

What is Hydroxyectoin?

Hydroxyectoin is supplied under the INCI / technical name Hydroxyectoin and carries CAS number 165542-32-9.

It belongs to the Extremolyte group and is available from synthetic, nature-identical, botanical or biotech routes depending on the grade ordered. The material reaches you as powder / liquid depending grade. It sits in the high-growth band of the 2025–2026 market, which means supply, pricing and claim substantiation are all moving quickly — confirm current availability before committing to a launch date.

Key Properties & Benefits

  • Stress protection
  • Hydration
  • Supplied cosmetic grade with a Certificate of Analysis for every batch.

Uses & Applications

Hydroxyectoin is used in barrier creams, ceramide moisturisers, post-procedure recovery products, sensitive-skin lotions, cleansing balms and overnight masks.

Typical applications from the catalogue record: Premium skin/scalp care.

In leave-on skincare it is normally dosed into a serum, ampoule or moisturiser where contact time is long enough for the claim to hold up. In rinse-off formats it is used at a lower level for label presence and sensory contribution rather than measurable performance.

How to Use — Recommended Use Level

Typical use level 0.3–2%
Recommended pH 3.0–9.0
Addition phase Water phase
Solubility Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

INCI / Technical Name Hydroxyectoin
CAS Number 165542-32-9
Ingredient Family Extremolyte
Primary Cosmetic Functions Stress protection; hydration
Typical Applications Premium skin/scalp care
Source / Feedstock Synthetic / nature-identical / botanical / biotech
Origin / Tradition Global
Typical Bulk Form Powder / liquid depending grade
Appearance Supplied as a powder or a liquid depending on the grade ordered
Solubility Water Soluble
Market Status Emerging 2025–2026
Catalogue Range Core Range
Storage Store in a tightly closed container at 15–25 °C, away from direct sunlight. Protect from freezing and from prolonged heat.
Shelf Life 24–36 months from manufacture in unopened original packaging; see the Certificate of Analysis
Vendor MakeYourSkin
MYS Catalogue Code COS-A00008

Regulatory Note

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

  • Certificate of Analysis (CoA) for the batch supplied
  • Safety Data Sheet (SDS / MSDS) in the current GHS format
  • Technical Data Sheet (TDS) with specification, solubility and handling guidance
  • INCI declaration and, where assigned, CAS / EINECS numbers
  • Non-GMO statement on request
  • Vegan / animal-origin declaration on request
  • Halal and Kosher certification on request where the supplier holds it
  • Heavy-metal and microbiological test data on request

Available Pack Sizes

This is a high-value material, so it is supplied on our small-pack ladder: 10 g, 50 g, 100 g and 1 Kg. Larger quantities are quoted on request — contact the MakeYourSkin sales desk for availability, lead time and a firm price.

10 g Bench trial, stability screening and claim work
50 g Pilot batches and small production runs
100 g Regular production for premium formulas
1 Kg Full production quantity; larger volumes quoted on request

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.

Specification

INCI NAMEHydroxyectoin
CAS NUMBER165542-32-9
FAMILYExtremolyte
ORIGINGlobal — Synthetic / nature-identical / botanical / biotech
SUPPLY FORMPowder / liquid depending grade
SOLUBILITYWater Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
TYPICAL USE LEVEL0.3–2%
pH RANGE3.0–9.0
ADD ATWater phase
FUNCTIONSStress protection; hydration
USED INPremium skin/scalp care
STORAGEStore in a tightly closed container at 15–25 °C, away from direct sunlight. Protect from freezing and from prolonged heat.
PACK SIZES10 g to 1 Kg
REGULATORYStandard cosmetic review

How to work with it

1 Check the phase before you weigh

The specification's Add at row is the one to read first. Water-phase materials added to a hot oil phase are the most common reason a batch separates.

2 Hold the pH inside the stated range

Measure the finished product, not the premix. Outside the range the activity drops away and, for some materials, the degradation route is what causes complaints.

3 Start at the bottom of the use level

Then work up through stability and compatibility testing. Higher is not better, and the destination market's limit may sit below your formulation ceiling.

Documents

No account needed
Allergen & Origin Declaration Issued per order Request

Documents for this material are issued on request and never gated behind an account — ask for the CoA, MSDS or TDS.