Biotinyl-GHK (Biotinoyl Tripeptide-1) is a Peptide supplied by MakeYourSkin as powder / liquid depending grade for professional cosmetic formulation. Used worldwide across mainstream cosmetic formulation, it is valued for hair anchoring support.

What is Biotinyl-GHK?

Biotinyl-GHK is supplied under the INCI / technical name Biotinoyl Tripeptide-1.

It belongs to the Peptide group and is available from synthetic, nature-identical, botanical or biotech routes depending on the grade ordered. The material reaches you as powder / liquid depending grade. It is an established cosmetic raw material with mature supply and well-understood formulation behaviour.

Key Properties & Benefits

• Hair anchoring support
• Supplied as a standardised solution so the finished-product dose can be calculated accurately.

Uses & Applications

Biotinyl-GHK is used in scalp serums, hair tonics, pre-wash oils, shampoos, conditioners, leave-in treatments and hair masks.

Typical applications from the catalogue record: Scalp serums, tonics, shampoos, conditioners.

In hair care it is split between rinse-off systems, where substantivity decides how much survives the rinse, and leave-on scalp serums and tonics, where the full dose stays on the scalp.

How to Use — Recommended Use Level

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

Regulatory Note

Confirm the exact INCI, the supplied concentration of active peptide, the carrier and preservative system, and the purity and residual-solvent profile. Peptide claim substantiation must match cosmetic claim rules; efficacy data generated in vitro or at levels above the finished-product concentration does not support a strong finished-product claim.

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

• Certificate of Analysis (CoA) for the batch supplied
• Safety Data Sheet (SDS / MSDS) in the current GHS format
• Technical Data Sheet (TDS) with specification, solubility and handling guidance
• INCI declaration and, where assigned, CAS / EINECS numbers
• Peptide purity, sequence confirmation and residual-solvent data
• Non-GMO statement on request
• Vegan / animal-origin declaration on request
• Halal and Kosher certification on request where the supplier holds it
• Heavy-metal and microbiological test data on request

Available Pack Sizes

This is a high-value material, so it is supplied on our small-pack ladder: 10 g, 50 g, 100 g and 1 Kg. Larger quantities are quoted on request — contact the MakeYourSkin sales desk for availability, lead time and a firm price.

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.

Heat-sensitive. Add at cool-down below the temperature stated on the technical data sheet; exceeding it degrades the active and can change colour and odour.