Azelaic Acid Derivative – Azeloyl Glycine (Potassium Azeloyl Diglycinate) — liquid, Global — MakeYourSkin

About this material

Azelaic Acid Derivative – Azeloyl Glycine (Potassium Azeloyl Diglycinate) is an Amino acid derivative supplied by MakeYourSkin as liquid / powder for professional cosmetic formulation. Used worldwide across mainstream cosmetic formulation, it is valued for sebum balance, tone-evening.

What is Azelaic Acid Derivative – Azeloyl Glycine?

Azelaic Acid Derivative – Azeloyl Glycine is supplied under the INCI / technical name Potassium Azeloyl Diglycinate and carries CAS number 477773-67-4.

It belongs to the Amino acid derivative group and is derived from azelaic acid and glycine. The material reaches you as liquid / powder. It is an established cosmetic raw material with mature supply and well-understood formulation behaviour.

Key Properties & Benefits

  • Sebum balance
  • Tone-evening
  • Supplied cosmetic grade with a Certificate of Analysis for every batch.

Uses & Applications

Azelaic Acid Derivative – Azeloyl Glycine is used in blemish serums, spot treatments, mattifying moisturisers, clay masks, purifying cleansers and toners.

Typical applications from the catalogue record: Blemish serums, rosacea-positioned care.

In leave-on skincare it is normally dosed into a serum, ampoule or moisturiser where contact time is long enough for the claim to hold up. In rinse-off formats it is used at a lower level for label presence and sensory contribution rather than measurable performance.

How to Use — Recommended Use Level

Typical use level 2–5%
Recommended pH 4.5–6.0
Addition phase Water phase
Solubility Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.

General rule: always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.

Technical Specification

INCI / Technical Name Potassium Azeloyl Diglycinate
CAS Number 477773-67-4
Ingredient Family Amino acid derivative
Primary Cosmetic Functions Sebum balance; tone-evening
Typical Applications Blemish serums, rosacea-positioned care
Source / Feedstock Azelaic acid and glycine
Origin / Tradition Global
Typical Bulk Form Liquid / powder
Appearance Supplied as a powder or a liquid depending on the grade ordered
Solubility Water Soluble
Market Status Established
Catalogue Range Core Range
Storage Store in a tightly closed container at 15–25 °C, away from direct sunlight. Protect from freezing and from prolonged heat.
Shelf Life 24–36 months from manufacture in unopened original packaging; see the Certificate of Analysis
Vendor MakeYourSkin
MYS Catalogue Code MYS-N00345

Technical Notes

Water-soluble and far easier to formulate than azelaic acid itself.

Regulatory Note

Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.

Reference: Regulatory / scientific reference

Documentation Supplied

  • Certificate of Analysis (CoA) for the batch supplied
  • Safety Data Sheet (SDS / MSDS) in the current GHS format
  • Technical Data Sheet (TDS) with specification, solubility and handling guidance
  • INCI declaration and, where assigned, CAS / EINECS numbers
  • Non-GMO statement on request
  • Vegan / animal-origin declaration on request
  • Halal and Kosher certification on request where the supplier holds it
  • Heavy-metal and microbiological test data on request

Available Pack Sizes

Supplied in 50 g, 225 g, 1 Kg and 5 Kg packs. Bulk quantities above 5 Kg, and drum or sack quantities, are available on request — contact the MakeYourSkin sales desk for a quotation and lead time.

50 g Pilot batches and small production runs
225 g Pilot batches and indie production runs
1 Kg Regular production for small and mid-size brands
5 Kg Scaled production and contract manufacturing

Disclaimer & Caution in Use

For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.

Low-pH material. Can cause burns to skin and eyes in concentrated form. Add to water, never water to acid; neutralise carefully and confirm the final pH of the finished product. Products formulated at low pH increase sun sensitivity — a daily sunscreen instruction is expected on the finished pack.

Fine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.

Can increase the skin's sensitivity to sunlight. The finished product should carry a daily broad-spectrum sunscreen instruction.

Specification

INCI NAMEPotassium Azeloyl Diglycinate
CAS NUMBER477773-67-4
FAMILYAmino acid derivative
ORIGINGlobal — Azelaic acid and glycine
SUPPLY FORMLiquid / powder
SOLUBILITYWater Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
TYPICAL USE LEVEL2–5%
pH RANGE4.5–6.0
ADD ATWater phase
FUNCTIONSSebum balance; tone-evening
USED INBlemish serums, rosacea-positioned care
STORAGEStore in a tightly closed container at 15–25 °C, away from direct sunlight. Protect from freezing and from prolonged heat.
PACK SIZES50 g to 5 Kg
LEAD TIME7–10 days
REGULATORYStandard cosmetic review

How to work with it

1 Check the phase before you weigh

The specification's Add at row is the one to read first. Water-phase materials added to a hot oil phase are the most common reason a batch separates.

2 Hold the pH inside the stated range

Measure the finished product, not the premix. Outside the range the activity drops away and, for some materials, the degradation route is what causes complaints.

3 Start at the bottom of the use level

Then work up through stability and compatibility testing. Higher is not better, and the destination market's limit may sit below your formulation ceiling.

Documents

No account needed
Allergen & Origin Declaration Issued per order Request

Documents for this material are issued on request and never gated behind an account — ask for the CoA, MSDS or TDS.