Restricted & High-Diligence Materials
For restricted cosmetic ingredients
Restricted & High-Diligence Materials
Materials that carry concentration limits, market restrictions or a cosmetic/drug boundary. Read the regulatory note on every product page before ordering.
This collection currently holds 76 raw materials. Most materials ship in 50 g, 225 g, 1 Kg and 5 Kg packs. High-value absolutes, isolates, ceramides and peptides ship on a small-pack ladder of 10 g, 50 g, 100 g and 1 Kg. Every pack comes with a Certificate of Analysis, SDS and technical data sheet.
Every product page lists the INCI or technical name, the CAS number where one is assigned, ingredient family, source and feedstock, origin, typical form, solubility, recommended use level and pH window, addition phase, market status, storage, shelf life, the documentation supplied and a full regulatory note.
Buying from MakeYourSkin
MakeYourSkin is building the largest quality-assured collection of cosmetic raw materials sourced from India, Korea, Japan and China. We supply indie brands, contract manufacturers, formulation labs and R&D teams worldwide. Prices are in USD; bulk quantities are quoted on request.
Before you formulate
Use levels shown on our product pages are industry working ranges, not specifications. Confirm every figure against the supplier technical data sheet, verify the permitted status and concentration limit in each market you sell into, and complete a safety assessment for the finished product.
Related collectionsClean Beauty · Animal-Derived Ingredients · Specialist & RFQ Materials · Natural Origin · Colour Cosmetics Ingredients
Powder / liquid
Phenethyl Alcohol
CAS 60-12-8Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $16.20
50 g – 5 Kg
Powder / liquid
Methylparaben
CAS 99-76-3Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $16.20
50 g – 5 Kg
Powder / liquid
Methylisothiazolinone
CAS 2682-20-4Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $13.50
50 g – 5 Kg
Powder / liquid
Methylchloroisothiazolinone
CAS 26172-55-4Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $13.50
50 g – 5 Kg
Powder / liquid
Iodopropynyl Butylcarbamate
CAS 55406-53-6Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $54.00
50 g – 5 Kg
Powder / liquid
Hydroxyacetophenone
CAS 99-93-4Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $27.00
50 g – 5 Kg
Powder / liquid
Ethylparaben
CAS 120-47-8Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $6.75
50 g – 5 Kg
Powder / liquid
Butylparaben
CAS 94-26-8Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $12.15
50 g – 5 Kg
Powder / stabilized dispersion
Sodium RNA
CAS 63231-63-0Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $64.80
10 g – 1 Kg
Powder / stabilized dispersion
Rose-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Rice-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Hydrolyzed DNA
CAS not assignedWater Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $202.50
50 g – 5 Kg
Powder / stabilized dispersion
Green Tea-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Ginseng-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Centella-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Aloe-Derived Extracellular VesiclesINCI Supplier-specific plant extracellular vesicles
CAS not assignedGrade Dependent — Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
In stock
from $141.75
10 g – 1 Kg
Powder / stabilized dispersion
Urolithin A
CAS 1143-70-0Glycol Soluble — Soluble in glycols (glycerin, propanediol, butylene glycol, propylene glycol) and in water-glycol blends. Pre-dissolve in the glycol before adding to the water phase.
In stock
from $249.75
10 g – 1 Kg
Powder / stabilized dispersion
Spermidine
CAS 124-20-9Water Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $182.25
10 g – 1 Kg
Powder / stabilized dispersion
Pyrroloquinoline Quinone
CAS 72909-34-3Water Dispersible — Water-dispersible rather than truly soluble. Sprinkle into vigorously stirred water or pre-wet in glycerin to avoid lumping.
In stock
from $357.75
10 g – 1 Kg
Powder / liquid
Polynucleotide Complex – Topical Grade (Sodium Polynucleotide)INCI Sodium Polynucleotide
CAS not assignedWater Soluble — Water-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.
In stock
from $182.25
10 g – 1 Kg
Powder / stabilized dispersion
Nicotinamide Riboside Topical (Nicotinamide Riboside)INCI Nicotinamide Riboside
CAS 23111-00-4Water Dispersible — Water-dispersible rather than truly soluble. Sprinkle into vigorously stirred water or pre-wet in glycerin to avoid lumping.
In stock
from $128.25
10 g – 1 Kg
Powder / stabilized dispersion
Nicotinamide Mononucleotide (NMN) Topical (Nicotinamide Mononucleotide)INCI Nicotinamide Mononucleotide
CAS 1094-61-7Water Dispersible — Water-dispersible rather than truly soluble. Sprinkle into vigorously stirred water or pre-wet in glycerin to avoid lumping.
In stock
from $113.40
10 g – 1 Kg
Powder / stabilized dispersion
NADH Topical (NADH)INCI NADH
CAS 606-68-8Water Dispersible — Water-dispersible rather than truly soluble. Sprinkle into vigorously stirred water or pre-wet in glycerin to avoid lumping.
In stock
from $283.50
10 g – 1 Kg
Powder / stabilized dispersion
ATP (Adenosine Triphosphate)INCI Adenosine Triphosphate
CAS 56-65-5Water Dispersible — Water-dispersible rather than truly soluble. Sprinkle into vigorously stirred water or pre-wet in glycerin to avoid lumping.
In stock
from $270.00
50 g – 5 Kg