About this material
Macrocyclic Musk Lactone (UNVERIFIED: Oxacyclohexadecan-2-one (11-oxahexadecanolide)) is macrocyclic lactone musk fragrance material supplied by MakeYourSkin as clear colourless to pale viscous liquid for professional cosmetic formulation. Sourced in the China / TCM tradition. It is valued for musk fragrance base note, fixative, substantivity on skin and fabric.
What is Macrocyclic Musk Lactone?
Macrocyclic Musk Lactone is supplied under the INCI / technical name UNVERIFIED: Oxacyclohexadecan-2-one (11-oxahexadecanolide).
It belongs to the Macrocyclic lactone musk fragrance material group. The material reaches you as clear colourless to pale viscous liquid. A macrocyclic (non-nitro, non-polycyclic) musk, the class favoured over restricted polycyclic musks; very high substantivity means small doses carry a long dry-down.
Key Properties & Benefits
- Musk fragrance base note
- Fixative
- Substantivity on skin and fabric
- Supplied with full documentation — CoA, SDS and specification
Uses & Applications
Typically formulated into fine fragrance, body care, hair fragrance, laundry-adjacent perfumery.
How to Use — Recommended Use Level
Typical use level: 0.1-5% of fragrance compound. Add at the grade-dependent — see the technical data sheet. Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating.
Always trial the material in your own base at small scale before scaling up. Use levels are formulation starting points, not approvals.
Technical Specification
- INCI name: UNVERIFIED: Oxacyclohexadecan-2-one (11-oxahexadecanolide)
- Ingredient family: Macrocyclic lactone musk fragrance material
- Origin / tradition: China / TCM
- Typical form: Clear colourless to pale viscous liquid
- Solubility: Grade Dependent
- Typical use level: 0.1-5% of fragrance compound
- pH range: 4.0–7.0
- Addition phase: Grade-dependent — see the technical data sheet
- Pack sizes: 50 g; 225 g; 1 Kg; 5 Kg; bulk on request
Technical Notes
A macrocyclic (non-nitro, non-polycyclic) musk, the class favoured over restricted polycyclic musks; very high substantivity means small doses carry a long dry-down.
Regulatory Note
Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.
Documentation Supplied
Certificate of Analysis (CoA) for the batch supplied; Safety Data Sheet (SDS / MSDS) in the current GHS format; INCI and technical specification sheet; allergen, GMO and origin statements on request; vegan, halal and kosher declarations where the supply chain supports them.
Available Pack Sizes
50 g; 225 g; 1 Kg; 5 Kg; bulk on request
Disclaimer & Caution in Use
For external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished product: do not apply it undiluted to skin or hair. Wear suitable gloves and eye protection when handling, weigh in a ventilated area, and keep out of reach of children. Patch test every finished formulation. Not for ingestion unless a food or oral-care grade is specifically supplied and documented as such. Seek medical advice in case of eye contact, ingestion or an adverse reaction. Highly concentrated aromatic material. Observe IFRA limits, declare allergens, and keep away from eyes and mucous membranes.
Specification
| INCI NAME | Oxacyclohexadecan-2-one (11-oxahexadecanolide) |
|---|---|
| CAS NUMBER | Not assigned |
| FAMILY | Macrocyclic lactone musk fragrance material |
| ORIGIN | China / TCM |
| SUPPLY FORM | Clear colourless to pale viscous liquid |
| SOLUBILITY | Solubility is grade-dependent. Confirm the exact carrier system and dilution route on the supplier technical data sheet before formulating. |
| TYPICAL USE LEVEL | 0.1-5% of fragrance compound |
| pH RANGE | 4.0–7.0 |
| ADD AT | Grade-dependent — see the technical data sheet |
| FUNCTIONS | Musk fragrance base note, fixative, substantivity on skin and fabric |
| USED IN | Fine fragrance, body care, hair fragrance, laundry-adjacent perfumery |
| STORAGE | Store at 15–25 °C in a tightly closed container, protected from light. Do not freeze. Some biological materials are supplied chilled — follow the batch documentation. |
| PACK SIZES | 50 g; 225 g; 1 Kg; 5 Kg; bulk on request |
| LEAD TIME | 10–16 days |
| REGULATORY | Sold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223/2009 and its Annexes; the United States applies the FD&C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment. |
How to work with it
The specification's Add at row is the one to read first. Water-phase materials added to a hot oil phase are the most common reason a batch separates.
Measure the finished product, not the premix. Outside the range the activity drops away and, for some materials, the degradation route is what causes complaints.
Then work up through stability and compatibility testing. Higher is not better, and the destination market's limit may sit below your formulation ceiling.