{"product_id":"polynucleotide-complex-topical-grade","title":"Polynucleotide Complex – Topical Grade (Sodium Polynucleotide)","description":"\u003cdiv class=\"mys-pdp\"\u003e\n\u003cp\u003e\u003cstrong\u003ePolynucleotide Complex – Topical Grade\u003c\/strong\u003e (Sodium Polynucleotide) is a Polynucleotide supplied by MakeYourSkin as powder \/ liquid for professional cosmetic formulation. A Korean-beauty staple, it is valued for hydration, conditioning, regenerative positioning.\u003c\/p\u003e\n\u003ch2\u003eWhat is Polynucleotide Complex – Topical Grade?\u003c\/h2\u003e\n\u003cp\u003ePolynucleotide Complex – Topical Grade is supplied under the INCI \/ technical name \u003cstrong\u003eSodium Polynucleotide\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eIt belongs to the \u003cstrong\u003ePolynucleotide\u003c\/strong\u003e group and is derived from salmon or trout milt derived. The material reaches you as powder \/ liquid. It sits in the high-growth band of the 2025–2026 market, which means supply, pricing and claim substantiation are all moving quickly — confirm current availability before committing to a launch date.\u003c\/p\u003e\n\u003ch2\u003eKey Properties \u0026amp; Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHydration\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eConditioning\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eRegenerative positioning\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003eSupplied cosmetic grade with a Certificate of Analysis for every batch.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eUses \u0026amp; Applications\u003c\/h2\u003e\n\u003cp\u003ePolynucleotide Complex – Topical Grade is used in anti-ageing serums, eye creams, night creams, ampoules, neck and décolleté treatments and firming body products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTypical applications from the catalogue record:\u003c\/strong\u003e Premium ampoules, post-procedure care.\u003c\/p\u003e\n\u003cp\u003eIn leave-on skincare it is normally dosed into a serum, ampoule or moisturiser where contact time is long enough for the claim to hold up. In rinse-off formats it is used at a lower level for label presence and sensory contribution rather than measurable performance. In Korean and Japanese formats it suits essences, toner pads, sheet-mask serums and lightweight gel-creams, where thin, layerable textures are the norm.\u003c\/p\u003e\n\u003ch2\u003eHow to Use — Recommended Use Level\u003c\/h2\u003e\n\u003ctable class=\"mys-table\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eTypical use level\u003c\/th\u003e\n\u003ctd\u003eNo single published figure applies to every grade of this material. As a working rule, start water-phase actives at 0.5–2%, oil-phase actives at 1–5%, standardised or potent isolates at 0.05–0.5%, and supplier-diluted solutions at the percentage the technical data sheet specifies. Always confirm the exact level against the supplier TDS, your stability and compatibility testing, and the safety assessment for your finished product.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eRecommended pH\u003c\/th\u003e\n\u003ctd\u003eformulation-dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAddition phase\u003c\/th\u003e\n\u003ctd\u003eAs per the supplier technical data sheet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSolubility\u003c\/th\u003e\n\u003ctd\u003eWater-soluble. Disperse into the water phase with stirring; avoid prolonged high heat where the material is heat-sensitive.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003cp\u003e\u003cem\u003eNo single published use level applies to every grade of this material, so the figure above is a general starting rule rather than a specification.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGeneral rule:\u003c\/strong\u003e always begin at the lower end of the range, confirm the level against the supplier technical data sheet, and validate stability, pH, colour, odour and preservative efficacy on the finished formulation before scaling up.\u003c\/p\u003e\n\u003ch2\u003eTechnical Specification\u003c\/h2\u003e\n\u003ctable class=\"mys-table\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eINCI \/ Technical Name\u003c\/th\u003e\n\u003ctd\u003eSodium Polynucleotide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003eConfirmed on the Certificate of Analysis for the exact grade supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient Family\u003c\/th\u003e\n\u003ctd\u003ePolynucleotide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePrimary Cosmetic Functions\u003c\/th\u003e\n\u003ctd\u003eHydration; conditioning; regenerative positioning\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTypical Applications\u003c\/th\u003e\n\u003ctd\u003ePremium ampoules, post-procedure care\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSource \/ Feedstock\u003c\/th\u003e\n\u003ctd\u003eSalmon or trout milt derived\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eOrigin \/ Tradition\u003c\/th\u003e\n\u003ctd\u003eKorea\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTypical Bulk Form\u003c\/th\u003e\n\u003ctd\u003ePowder \/ liquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAppearance\u003c\/th\u003e\n\u003ctd\u003eSupplied as a powder or a liquid depending on the grade ordered\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSolubility\u003c\/th\u003e\n\u003ctd\u003eWater Soluble\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMarket Status\u003c\/th\u003e\n\u003ctd\u003eHigh-growth 2025–2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalogue Range\u003c\/th\u003e\n\u003ctd\u003eCore Range\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eStore in a tightly closed container at 15–25 °C, away from direct sunlight. Protect from freezing and from prolonged heat.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eShelf Life\u003c\/th\u003e\n\u003ctd\u003e24–36 months from manufacture in unopened original packaging; see the Certificate of Analysis\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eVendor\u003c\/th\u003e\n\u003ctd\u003eMakeYourSkin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMYS Catalogue Code\u003c\/th\u003e\n\u003ctd\u003eMYS-N00096\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eTechnical Notes\u003c\/h2\u003e\n\u003cp\u003eThe single hottest K-beauty ingredient story of 2025–2026. Cosmetic claims only — injectable evidence does not transfer.\u003c\/p\u003e\n\u003ch2\u003eRegulatory Note\u003c\/h2\u003e\n\u003cp\u003eSupplier diligence required: High diligence: source species, molecular weight, purity, claims and jurisdiction-specific review.\u003c\/p\u003e\n\u003cp\u003eSold as a cosmetic raw material for professional formulation. A published INCI name does not by itself authorise use: the buyer is responsible for confirming permitted status, maximum concentration, restrictions by product type, labelling and claim rules in every market the finished product is sold in. In India, cosmetics fall under the Drugs and Cosmetics Act 1940 and the Cosmetics Rules 2020 administered by CDSCO, with BIS standards (including IS 4707 Part 2) listing restricted substances. The EU applies Regulation (EC) No 1223\/2009 and its Annexes; the United States applies the FD\u0026amp;C Act as amended by MoCRA; Korea, Japan and China operate their own positive lists and functional-cosmetic frameworks. Every finished product needs its own safety assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReference:\u003c\/strong\u003e \u003ca href=\"https:\/\/single-market-economy.ec.europa.eu\/sectors\/cosmetics\/cosmetic-ingredient-database_en\" rel=\"nofollow noopener\" target=\"_blank\"\u003eRegulatory \/ scientific reference\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eDocumentation Supplied\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCertificate of Analysis (CoA) for the batch supplied\u003c\/li\u003e\n\u003cli\u003eSafety Data Sheet (SDS \/ MSDS) in the current GHS format\u003c\/li\u003e\n\u003cli\u003eTechnical Data Sheet (TDS) with specification, solubility and handling guidance\u003c\/li\u003e\n\u003cli\u003eINCI declaration and, where assigned, CAS \/ EINECS numbers\u003c\/li\u003e\n\u003cli\u003eNon-GMO statement on request\u003c\/li\u003e\n\u003cli\u003eVegan \/ animal-origin declaration on request\u003c\/li\u003e\n\u003cli\u003eHalal and Kosher certification on request where the supplier holds it\u003c\/li\u003e\n\u003cli\u003eHeavy-metal and microbiological test data on request\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAvailable Pack Sizes\u003c\/h2\u003e\n\u003cp\u003eThis is a high-value material, so it is supplied on our small-pack ladder: \u003cstrong\u003e10 g, 50 g, 100 g and 1 Kg\u003c\/strong\u003e. Larger quantities are quoted on request — contact the MakeYourSkin sales desk for availability, lead time and a firm price.\u003c\/p\u003e\n\u003ctable class=\"mys-table\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e10 g\u003c\/th\u003e\n\u003ctd\u003eBench trial, stability screening and claim work\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e50 g\u003c\/th\u003e\n\u003ctd\u003ePilot batches and small production runs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e100 g\u003c\/th\u003e\n\u003ctd\u003eRegular production for premium formulas\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e1 Kg\u003c\/th\u003e\n\u003ctd\u003eFull production quantity; larger volumes quoted on request\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eDisclaimer \u0026amp; Caution in Use\u003c\/h2\u003e\n\u003cp\u003eFor external cosmetic use in professionally formulated products only. This is a concentrated raw material, not a finished cosmetic, and it is not intended for undiluted application to skin, for ingestion, or for any medicinal purpose. Wear gloves and eye protection when handling, avoid raising dust with powders, and keep out of reach of children and pets. Always run a patch test on the finished formulation, and validate stability, compatibility, pH and preservative efficacy before sale. Information supplied is offered in good faith as formulation guidance and does not constitute a safety assessment, a regulatory approval or a medical claim.\u003c\/p\u003e\n\u003cp\u003eFine powder — avoid generating and inhaling dust. Use local exhaust ventilation or a suitable respirator when weighing, and wet the powder into the formulation phase rather than dry-blending in open air.\u003c\/p\u003e\n\u003cp\u003eRestricted or high-diligence material. Confirm your legal position in every destination market before ordering. Supplied on the understanding that the buyer holds responsibility for compliant use, permitted concentration and claim wording.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"MakeYourSkin","offers":[{"title":"10 g","offer_id":47681090912418,"sku":"MYS-N00096-10G","price":182.25,"currency_code":"USD","in_stock":true},{"title":"50 g","offer_id":47681090945186,"sku":"MYS-N00096-50G","price":533.25,"currency_code":"USD","in_stock":true},{"title":"100 g","offer_id":47681090977954,"sku":"MYS-N00096-100G","price":891.0,"currency_code":"USD","in_stock":true},{"title":"1 Kg","offer_id":47681091010722,"sku":"MYS-N00096-1000G","price":4428.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0733\/0879\/9138\/files\/polynucleotide-complex-topical-grade-01_d483fb1b-d4d9-49a9-a91d-128584054d3c.webp?v=1789800591","url":"https:\/\/makeyourskin.com\/products\/polynucleotide-complex-topical-grade","provider":"MakeYourSkin","version":"1.0","type":"link"}